Are headaches a side effect of Champix? Side effects of Champix It may help to take Champix with food, or your doctor may reduce the dose. Less common side effects include stomach or bowel problems (e.g. constipation, gas, dry mouth, vomiting, indigestion), headache, dizziness, feeling tired, increased appetite and changes in taste. What is the active ingredient in Zyban? Zyban's active ingredient is bupropion, the antidepressant medication sold as Wellbutrin. While Wellbutrin and other antidepressants have labels warning of suicidal thoughts, the warning had not been fully extended to people taking Zyban to quit smoking.
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